Definition of "anathema"

Even three years ago, the thought of spending two hours, let alone a whole day, without my mobile would have been anathema.

2015 January 18, Monty Munford, “What’s the point of carrying a mobile phone nowadays?”, in The Daily Telegraph‎

The actor, who prizes mystery, hated being gossip fodder. “That was anathema to him,” said his sister Martha Fiennes, a filmmaker, “and he just hated the curiosity into his life.”

2022 October 22, Maureen Dowd, “Ralph Fiennes, Master of Monsters”, in The New York Times‎

I trembled at his ringing wealthOf manifold anathemas […]

1920, Edward Arlington Robinson, “The Wandering Jew”, in The Three Taverns

That was a curse from which no flight was possible: the anathema of a man who had once known holiness.

2002, Joseph O'Conner, Star of the Sea, Vintage, published 2003, page 30

If any man love not the Lord Jesus Christ, let him be Anathema Maranatha.

1611, The Holy Bible, […] (King James Version), London: […] Robert Barker, […], 1 Corinthians 16:22

Ἆνάθεμα, accurẛed, חרם, which the Septuagint renders Anathema, ẛignifies Perẛons or Things devoted to Deẛtruction and Extermination. The Jewiẛh Nation were now an Anathema, deẛtin'd to Deẛtruction. St. Paul to expreẛs his Affection to them, ẛays, he could wiẛh to ẛave them from it, to become an Anathema and be deẛtroy'd himẛelf.

1707, John Locke, “The Epistle of St. Paul to the Romans”, in An Essay for Understanding St. Paul's Epistles, by Consulting St. Paul Himself, Section VIII

If any one refuses to confess that the Word of God the Father is united in hypostasis to flesh, and is one Christ with His own flesh, the same being at once both God and man, let him be anathema.

1885, “The Anathemas of Cyril in Opposition to Nestorius”, in Philip Schaff, editor, Nicene and Post-Nicene Fathers (II), volume III