Definition of "deperdition"

For the activity of the agent, being not able to overmaſter the reſiſtance of the patient, there will enſue no deperdition.

1646, Thomas Browne, “Of the Cameleon”, in Pseudodoxia Epidemica: […], London: […] T[homas] H[arper] for Edward Dod, […], 3rd book, page 163

After the deperdition of Indagator, having an appetency still further to pervstigate the frithy occident; being still an agamist, and not wishing to be any longer a pedaneous viator, nor to be solivagant, I brought about the emption of a yaud, partly by numismatic mutuation, and partly by a hypothecation of my fusee and argental horologe.

1856, Samuel Klinefelter Hoshour, Letters to Squire Pedant, in the East, page 28