Definition of "depolarization"

The act of reducing polarity, or the result of such action; reduction to an unpolarized or less polarized condition.

1. (biology, medicine) An intracellular shift in electrical charge distribution, resulting in less negative charge inside the cell compared with outside; it is essential to the function of many cells, communication between cells, and the overall physiology of an organism.

2. (sociology) Reduction of political polarization.