Definition of "out of tune"

out of tune

prepositional phrase
1. Not in the correct musical pitch.
  Quotations
  It is the lark that sings so out of tune,Straining harsh discords and unpleasing sharps.
  c. 1591–1595 (date written), William Shakespeare, “The Tragedie of Romeo and Ivliet”, in Mr. William Shakespeares Comedies, Histories, & Tragedies […] (First Folio), London: […] Isaac Iaggard, and Ed[ward] Blount, published 1623, [Act III, scene v]
2. (figurative) Not in agreement or in harmony (with something).
  Quotations
  […] a house which is aping the town fashions of Germany and France, a prim, hideous, straight-up-and-down thing, plastered all over on the outside to look like stone, and altogether so stiff, and formal, and ugly and forbidding, and so out of tune with the gracious landscape, and so deaf and dumb and dead to the poetry of its surroundings, that it suggests an undertaker at a picnic, a corpse at a wedding, a puritan in Paradise.
  1880, Mark Twain [pseudonym; Samuel Langhorne Clemens], chapter 31, in A Tramp Abroad; […], Hartford, Conn.: American Publishing Company; London: Chatto & Windus, page 324