Definition of "rube"

"Same time," said Babbitt, "no sense excusing these rube burgs too easy. Fellow's own fault if he doesn't show the initiative to up and beat it to the city, like we done—did. […] "

1922, Sinclair Lewis, chapter 8, in Babbitt, New York, N.Y.: Harcourt, Brace and Company

You know what you look like to me, with your good bag and your cheap shoes? You look like a rube. A well scrubbed, hustling rube with a little taste.

1991, Ted Tally, The Silence of the Lambs (motion picture), spoken by Hannibal Lecter (Anthony Hopkins)