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(historical) Initialism of Brotherhood (of) Railway Carmen of America.
countable and uncountable, plural BRCAs
(biochemistry) Any of a number of genes and proteins associated with breast cancer, especially BRCA1 and BRCA2. quotations examples
The writer David Samuels, a friend since childhood, said the cause was metastatic breast cancer, which in her case had resulted from the BRCA genetic mutation. Ms. Wurtzel had a double mastectomy in 2015. After her diagnosis, she became an advocate for BRCA testing — something she had not had — and wrote about her cancer experience in The New York Times.
2020 January 7, Neil Genzlinger, “Elizabeth Wurtzel, ‘Prozac Nation’ Author, Is Dead at 52”, in The New York Times