Definition of "anxiogenic"

A CRF antagonist, -helical CRF(9-41), can also attenuate the anxiogenic behavioral effects of HU-210.

1997 June 27, “Activation of Corticotropin-Releasing Factor in the Limbic System During Cannabinoid Withdrawal”, in Science, volume 276, number 5321, pages 2050–2054

Increases in dopamine efflux in the NAS cannot simply be seen as equivalent to drug reward, because aversive stimuli, such as foot shock, and anxiogenic drugs, such as FG 7142 and beta-CCE (which are not self-administered), have exactly the same neurochemical effect (3 ).

1997 August 8, Lester Grinspoon et al., “Marijuana Addiction”, in Science, volume 277, number 5327, pages 749–753

Central injection of substance P or related peptide agonists induces conditioned place aversion and produces an anxiogenic profile on the elevated plus maze, implying that activation of central substance P pathways is aversive (5 ).

1998 September 11, Mark S. Kramer et al., “Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors”, in Science, volume 281, number 5383, pages 1640–1645

Thus, self-directed behavior increases after anxiogenic drug treatment but decreases after anxiolytic drug treatment (29 ).

2000 July 28, Frans B. M. de Waal, “Primates--A Natural Heritage of Conflict Resolution”, in Science, volume 289, issue 5479, 586-590

This piece will perform a micro-excavation of these toplayers of the literary soil to suggest anxiogenic literature has the potential not only to adumbrate the post-apocalypse, a common theme in contemporary literature, but also to anticipate the post-Anthropocene.

2020, Kristen Figgins, “The Integrity of Nature”, in Jonathan Elmore, editor, Fiction and the Sixth Mass Extinction, Rowman & Littlefield