Definition of "mandrake"

(mythology) A mandragora, a kind of tiny demon immune to fire.

Any plant of the genus Mandragora, certain of which are said to have medicinal or aphrodisiac properties; the root of these plants often resembles the shape of a small person, hence occasioning various mythic, magical, or occult uses.  examples

A root of a mandrake plant that resembled human form, especially one kept or used for magic or occult purposes.  quotations  examples

(slang) The drug methaqualone.